September was a big month for the acquisition of Israeli companies in the international marketplace, with six big deals going through during the High Holiday season, according to a report by Israel21c.

Ireland’s Medtronic purchased the Caesarea-based Mazor Robotics, which pioneered robotic guidance systems for brain and spinal surgeries, for a whopping $1.64 billion.

The Tel Aviv-based Upstream Commerce will remain in Israel, but was purchased for approximately $45 million by India’s largest e-commerce marketplace Flipkart, as a maker of cloud-based, real-time automated pricing and product assortment solutions.

Online mobile food-ordering and delivery marketplace Grubhub will pay $150 million to buy Tapingo, an Israeli-based platform for campus food-ordering at 1,550 university, college and professional campuses in the United States.

Venus Medtech of Hangzhou, China, a transcatheter heart-valve device-maker, has signed an agreement to buy Caesarea-based Keystone Heart, which developed the first cerebral embolic protection device designed to provide complete brain protection for patients undergoing cardiac procedures. The amount of the sale was not disclosed.

American software development and operations leader JFrog will acquire technology consulting company Trainologic of Herzliya. Financial details were not disclosed.

American surgical-robotics systems company TransEnterix will buy Yokneam Illit’s Medical Surgery Technologies for $12.4 million, in addition to 3.15 million shares of TransEnterix stock. It will also acquire a software-based image analytics platform powered by artificial intelligence, machine learning and data analytics.

The company will stay in Israel, but become TransEnterix Israel.